SCHEMBL891582

SCHEMBL891582

C=Cc1ccc(CC(C)[Zn])cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.36
HDAC8 Q9BY41 1/20 0.35
SLC6A4 P31645 1/20 0.34
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
SLC6A2 P23975 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
SLC6A3 Q01959 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL546949 0.83 ALDH1A1 (0.50) ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL28640315 0.81 ALDH1A1 (0.48) ALDH1A1TSHR
SCHEMBL570118 0.81 ALDH1A1 (0.48) ALDH1A1TSHRHDAC8SLC6A4TAS1R3
SCHEMBL5039218 0.79 ALDH1A1 (0.46) ALDH1A1TSHRHDAC8SLC6A4TAS1R3
SCHEMBL3677179 0.79 ALDH1A1 (0.46) ALDH1A1TSHRHDAC8SLC6A4TAS1R3
SCHEMBL9158412 0.79 TAAR1 (0.55) SLC6A4TAAR1SLC6A2SLC6A3
SCHEMBL30200150 0.78 ALDH1A1 (0.50) ALDH1A1TSHRHDAC8SLC6A4TAS1R3
SCHEMBL5197835 0.78 ALDH1A1 (0.44) ALDH1A1TSHRHDAC8SLC6A4TAS1R3
SCHEMBL13958796 0.78 ALDH1A1 (0.44) ALDH1A1TSHRHDAC8SLC6A4TAS1R3
SCHEMBL5039083 0.78 ALDH1A1 (0.44) ALDH1A1TSHRHDAC8SLC6A4TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120083575-A1 COMB ARCHITECTURE OLEFIN BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 US claimed
EP-2436703-B1 Comb architecture olefin block copolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-25 EP disclosed
US-8907034-B2 Comb architecture olefin block copolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-09 US disclosed
EP-1940896-B1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT DOW GLOBAL TECHNOLOGIES LLC (US) 2014-10-22 EP disclosed
US-8415434-B2 Catalytic olefin block copolymers via polymerizable shuttling agent DOW GLOBAL TECHNOLOGIES LLC (US) 2013-04-09 US disclosed
US-20120083575-A1 COMB ARCHITECTURE OLEFIN BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 US disclosed
US-20110092651-A1 Catalytic Olefin Block Copolymers Via Polymerizable Shuttling Agent ARRIOLA DANIEL J 2011-04-21 US disclosed
US-7858707-B2 Catalytic olefin block copolymers via polymerizable shuttling agent DOW GLOBAL TECHNOLOGIES INC. (US) 2010-12-28 US disclosed
US-20090163667-A1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT DOW GLOBAL TECHNOLOGIES INC. (US) 2009-06-25 US disclosed
EP-1940896-A1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT Dow Global Technologies Inc. (US) 2008-07-09 EP disclosed
WO-2007035492-A1 CATALYTIC OLEFIN BLOCK COPOLYMERS VIA POLYMERIZABLE SHUTTLING AGENT DOW GLOBAL TECHNOLOGIES INC. (US) 2007-03-29 WO disclosed