SCHEMBL546949

SCHEMBL546949

C=Cc1ccc(CC(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
PTGS1 P23219 3/20 0.42
PTGS2 P35354 3/20 0.42
LMNA P02545 2/20 0.42
CYP2C9 P11712 2/20 0.42
AKR1C3 P42330 2/20 0.42
CXCR1 P25024 2/20 0.42
CXCR2 P25025 2/20 0.42
ALB P02768 1/20 0.42
ESR1 P03372 1/20 0.42
ALOX5 P09917 1/20 0.42
RARB P10826 1/20 0.42
ADRB3 P13945 1/20 0.42
NFKB1 P19838 1/20 0.42
HTR2A P28223 1/20 0.42
NR1I3 Q14994 1/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
CXCL8 P10145 1/20 0.42
TSHR P16473 1/20 0.42
AKR1C2 P52895 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28640315 0.98 ALDH1A1 (0.48) ALDH1A1PTGS1PTGS2LMNACYP2C9
SCHEMBL570118 0.84 ALDH1A1 (0.48) ALDH1A1ESR1TSHRNPC1RAB9A
SCHEMBL3677179 0.83 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL5039218 0.83 ALDH1A1 (0.46) ALDH1A1PTGS2LMNACYP2C9ESR1
SCHEMBL891582 0.83 ALDH1A1 (0.46) ALDH1A1TSHR
SCHEMBL9158412 0.83 TAAR1 (0.55)
SCHEMBL30200150 0.82 ALDH1A1 (0.50) ALDH1A1TSHRMEN1POLBKMT2A
SCHEMBL9576148 0.81 NPC1 (0.51) ALDH1A1PTGS1PTGS2LMNACYP2C9
SCHEMBL7185145 0.81 NPC1 (0.51) ALDH1A1PTGS1PTGS2LMNACYP2C9
SCHEMBL7185147 0.81 NPC1 (0.51) ALDH1A1PTGS1PTGS2LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637532-B2 Sulfonated polymers and compositions thereof Kraton Corporation (US) 2026-05-26 US claimed
US-12559619-B2 Styrenic block copolymers and methods of preparation thereof Kraton Corporation (US) 2026-02-24 US claimed
US-20250277113-A1 PROCESS FOR PRODUCING OXIDIZED BITUMEN COMPOSITIONS Kraton Corporation (US) 2025-09-04 US claimed
EP-4265678-B1 HYDROGENATED STYRENIC BLOCK COPOLYMERS AND COMPOSITIONS THEREOF KRATON POLYMERS NEDERLAND B V (NL) 2025-07-09 EP claimed
EP-4141065-B1 OLEFIN-AROMATIC VINYL COMPOUND-AROMATIC POLYENE, CURABLE COMPOSITION COMPRISING THE SAME, AND CURED PRODUCT THEREOF DENKA COMPANY LTD (JP) 2025-07-09 EP claimed
CN-119875426-A Pure water-based ink for films, preparation method thereof and application thereof in gravure printing and flexographic printing 七彩新材料科技(河北)有限公司 2025-04-25 CN claimed
CN-119874494-A CO (carbon monoxide)2Switch type surfactant mediated olefin water two-phase hydroformylation method 青岛科技大学 2025-04-25 CN claimed
CN-119684346-A Preparation method of selective beta-silicon-based aryl acetic acid compound 扬州大学 2025-03-25 CN claimed
EP-4520772-A1 SULFONATED STYRENIC BLOCK COPOLYMER SEPARATOR AND ENERGY STORAGE DEVICE Notark Corporation (US) 2025-03-12 EP claimed
CN-119569973-A Sulfonated styrenic block copolymer membrane and energy storage device 诺塔克公司 2025-03-07 CN claimed
EP-0170147-B1 METHOD FOR PRODUCING ALPHA-(P-ISOBUTYLPHENYL)PROPIONIC ACID OR ITS ALKYL ESTERS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-01-18 EP claimed
EP-0293633-A2 1,2-Di(4-isobutylphenyl)ethylene and its preparation and use as intermediate NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-12-07 EP claimed
WO-1988008835-A1 ASYMMETRIC HYDROFORMYLATIONS OF PROCHIRAL OLEFINS TO CHIRAL ALDEHYDES IN HIGH ENANTIOMERIC EXCESS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1988-11-17 WO claimed
EP-0290050-A1 Method for producing alkylstyrene NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-11-09 EP claimed
US-4694100-A CATALYTIC CRACKING OF 1,1-BIS(P-ISOBUTYLPHENYL) ETHYLENE, THEN CARBONYLATION NIPPON PETROCHEMICALS COMPANY, LTD. (JP) 1987-09-15 US claimed
EP-0170147-A1 Method for producing alpha-(p-isobutylphenyl)propionic acid or its alkyl esters NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-02-05 EP claimed
EP-0168803-A2 Method for producing p-Isobutylstyrene NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-01-22 EP claimed
US-4327191-A THEN AMINATING RHONE-POULENC INDUSTRIES (FR) 1982-04-27 US claimed
EP-0025385-A1 Preparation of anion-exchange resins by bromination of vinylaromatic polymers, and products obtained RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-03-18 EP claimed
US-4156034-A COPOLYMER OF ACRYLIC ESTER AND STYRENE DERIVATIVE AS COATING AGENT HITACHI, LTD. (JP) 1979-05-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637532-B2 Sulfonated polymers and compositions thereof PCNA, SDC1, MSH2 ALDH1A1 2232/4885PTGS1 588/4885PTGS2 743/4885
US-12559619-B2 Styrenic block copolymers and methods of preparation thereof HSPB1, SDC1, TGFBR1 ALDH1A1 1682/4885PTGS1 429/4885PTGS2 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.