Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
| ▸ | FDPS | P14324 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2558697 | 0.92 | SMPD1 (0.44) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3627331 | 0.88 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3628004 | 0.88 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL29222649 | 0.88 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8882237 | 0.88 | DNM1 (0.57) | DNM1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL18400700 | 0.83 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL6200765 | 0.81 | TP53 (0.41) | EPHX1FDPSTP53 | |
| Sulfuric Acid SCHEMBL11297635 | 0.81 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Tetradecylamine SCHEMBL6552384 | 0.81 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Sulfuric Acid SCHEMBL20515717 | 0.81 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9171090-A | — | — | None | — | — | JP | disclosed |
| JP-H09171090-A | MANUFACTURE OF NUCLEAR FUEL PELLET COMPOSED MAINLY OF MIXED OXIDE OF URANIUM AND PLUTONIUM AND CONTAINING ORGANIC SULFUR COMPOUND AS ADDITIVE | COMMISS ENERG ATOM | 1997-06-30 | — | — | JP | disclosed |