SCHEMBL8915849

SCHEMBL8915849

CCCCCCCCN(CCCCCCCC)S(=O)(=O)c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GLA P06280 1/20 0.46
HTR2A P28223 3/20 0.45
HTR2C P28335 3/20 0.45
HTR7 P34969 2/20 0.45
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
HTT P42858 1/20 0.44
HIF1A Q16665 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A9 P48067 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
KDM4E B2RXH2 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3701072 0.94 TSHR (0.56) TSHRKEAP1NFE2L2MEN1KMT2A
SCHEMBL14415467 0.82 HTT (0.54) TSHRKEAP1NFE2L2MEN1KMT2A
SCHEMBL18320608 0.82 CNR2 (0.61) CNR1CNR2
SCHEMBL6412206 0.82 CYP1A2 (0.70) TSHRMEN1KMT2AGLACYP1A2
Dodecane SCHEMBL7645849 0.81 SCN1A (0.49) TSHRMEN1KMT2ACYP1A2CYP2C19
SCHEMBL11692098 0.81 LDHA (0.49) TSHRMEN1KMT2AGLACYP1A2
SCHEMBL13979927 0.81 HTT (0.64) TSHRKEAP1NFE2L2MEN1KMT2A
SCHEMBL20314709 0.81 HTR2A (0.47) TSHRKEAP1NFE2L2HTR2AHTR2C
SCHEMBL7323341 0.80 ROCK2 (0.54) TSHRMEN1KMT2AGLAHIF1A
SCHEMBL7326840 0.80 ROCK2 (0.54) TSHRMEN1KMT2AGLAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5591503-A Magnetic recording medium having a thin film magnetic layer and a sulfonamide lubricant THE DOW CHEMICAL COMPANY (US) 1997-01-07 US disclosed