Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801960 | 0.86 | NPSR1 (0.43) | KDM4ESYKALDH1A1HPGDMAPT | |
| SCHEMBL6801964 | 0.86 | NPSR1 (0.43) | KDM4ESYKALDH1A1HPGDMAPT | |
| SCHEMBL8983588 | 0.80 | SLC9A1 (0.61) | — | |
| SCHEMBL8983614 | 0.80 | SLC9A1 (0.61) | — | |
| SCHEMBL8983581 | 0.79 | SLC9A1 (0.38) | SYK | |
| SCHEMBL8983574 | 0.79 | SLC9A1 (0.38) | SYK | |
| SCHEMBL8983612 | 0.79 | SLC9A1 (0.38) | SYK | |
| SCHEMBL8816182 | 0.74 | VCAM1 (0.50) | VCAM1CMA1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8918126 | 0.74 | CA12 (0.65) | VCAM1CMA1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL27652105 | 0.73 | VCAM1 (0.52) | VCAM1CMA1KDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670544-A | ANTIISCHEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |