Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915843 | 0.83 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL8618280 | 0.79 | ITGB3 (0.34) | ITGB3ITGA2B | |
| SCHEMBL9056746 | 0.74 | ITGB3 (0.42) | ITGB3ITGA2BSIGMAR1F2R | |
| SCHEMBL9063434 | 0.73 | ITGB3 (0.69) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL3981005 | 0.73 | ITGB3 (0.69) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL7159970 | 0.68 | ITGB3 (0.49) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL24322585 | 0.66 | ITGB3 (0.66) | ITGB3ITGA2BF2F10F2R | |
| SCHEMBL6886518 | 0.65 | ITGB3 (1.00) | ITGB3ITGA2BF2F10F2R | |
| SCHEMBL13039757 | 0.65 | ITGB3 (0.71) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL9112266 | 0.63 | ITGB3 (0.70) | ITGB3ITGA2BF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684018-A | Acyloxyisopropyl carbamates as prodrugs for amine drugs | MERCK & CO., INC. (US) | 1997-11-04 | — | — | US | claimed |
| US-5684018-A | Acyloxyisopropyl carbamates as prodrugs for amine drugs | MERCK & CO., INC. (US) | 1997-11-04 | — | — | US | disclosed |