SCHEMBL8916208

SCHEMBL8916208

CN(c1ccccc1)c1ccccc1S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.44
NR3C2 P08235 1/20 0.42
MYC P01106 1/20 0.40
MCOLN3 Q8TDD5 1/20 0.39
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CA12 O43570 3/20 0.38
CA9 Q16790 3/20 0.38
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
CA4 P22748 1/20 0.38
TTR P02766 1/20 0.38
PTPN1 P18031 1/20 0.38
CES1 P23141 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27530800 0.88 NPC1 (0.40) HTR6NR3C2MYCTSHRSMN1; SMN2
SCHEMBL26630550 0.85 TTR (0.44) HTR6NR3C2MYCMCOLN3CA12
SCHEMBL14266725 0.84 TTR (0.49) HTR6NR3C2MYCMCOLN3CA2
SCHEMBL3281847 0.81 TSHR (0.41) HTR6MYCTSHRSMN1; SMN2CA2
SCHEMBL6265807 0.80 HTR6 (0.60) HTR6MYCTSHRSMN1; SMN2CA12
SCHEMBL28326313 0.79 HTR6 (0.58) HTR6MYCTSHRSMN1; SMN2CA12
SCHEMBL8015799 0.78 TTR (0.42) HTR6MYCTSHRSMN1; SMN2CA2
SCHEMBL7155151 0.75 MEN1 (0.46) NR3C2SMN1; SMN2CA12CA9CA2
SCHEMBL3987154 0.74 HTR6 (0.41) HTR6MYCTSHRSMN1; SMN2CA12
SCHEMBL4249310 0.73 ALDH1A1 (0.50) MYCTSHRSMN1; SMN2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5599911-A Fiber-reactive dyes having a central 1,3,5-triazine ring to which are bonded to a monoazo chromophore having another 1,3,5-triazine moiety and a second chromophore CIBA-GEIGY CORPORATION (US) 1997-02-04 US disclosed