Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 13/20 | 0.48 |
| ▸ | HRH2 | P25021 | 9/20 | 0.48 |
| ▸ | HRH1 | P35367 | 5/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918930 | 0.99 | HRH4 (0.48) | HRH4HRH2HRH1HRH3CYP1A2 | |
| SCHEMBL8915041 | 0.92 | HRH4 (0.53) | HRH4HRH2HRH1HRH3CYP1A2 | |
| SCHEMBL8918620 | 0.84 | MAPT (0.45) | HRH4HRH2HRH1HRH3ALDH1A1 | |
| SCHEMBL6950781 | 0.83 | CYP3A4 (0.46) | HRH4HRH2HRH3CYP3A4CYP2D6 | |
| SCHEMBL8918750 | 0.82 | HRH4 (0.41) | HRH4HRH2HRH3ALDH1A1 | |
| SCHEMBL8054318 | 0.82 | CYP3A4 (0.47) | HRH4HRH2HRH3CYP3A4CYP2D6 | |
| SCHEMBL8054097 | 0.82 | CYP3A4 (0.47) | HRH4HRH2HRH3CYP3A4CYP2D6 | |
| SCHEMBL504459 | 0.82 | CYP3A4 (0.47) | HRH4HRH2HRH3CYP3A4CYP2D6 | |
| SCHEMBL504458 | 0.82 | CYP3A4 (0.47) | HRH4HRH2HRH3CYP3A4CYP2D6 | |
| SCHEMBL504466 | 0.82 | CYP3A4 (0.47) | HRH4HRH2HRH3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696140-A | FOR TREATMENT OF ASTHMA, ALLERGIES, NERVOUS SYSTEM DISORDERS OR CANCER | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1997-12-09 | — | — | US | disclosed |