SCHEMBL891623

SCHEMBL891623

CCCCCCCCCCCCn1nc2c(Br)ccc(Br)c2n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 3/20 0.42
CSNK2B P67870 3/20 0.42
CSNK2A1 P68400 3/20 0.42
CSNK2A3 Q8NEV1 3/20 0.42
GRM2 Q14416 1/20 0.41
NPC1 O15118 5/20 0.37
RAB9A P51151 5/20 0.37
HTT P42858 4/20 0.37
GALR3 O60755 2/20 0.37
POLB P06746 2/20 0.37
ATM Q13315 2/20 0.37
MAPK1 P28482 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPT P10636 1/20 0.37
RAD52 P43351 1/20 0.37
PAX8 Q06710 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3531742 1.00 CSNK2A2 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3GRM2
SCHEMBL14799733 1.00 CSNK2A2 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3GRM2
SCHEMBL31493127 0.92 GRM2 (0.46) CSNK2A2CSNK2BCSNK2A1CSNK2A3GRM2
SCHEMBL16204112 0.84 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3TOP2A
SCHEMBL16204094 0.84 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3TOP2A
SCHEMBL19073356 0.84 GRM2 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3GRM2
SCHEMBL27896100 0.84 GRM2 (0.44) CSNK2A2CSNK2BCSNK2A1CSNK2A3GRM2
SCHEMBL17281154 0.83 CSNK2A1 (0.43) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL19138019 0.81 CSNK2A1 (0.42) CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL16252135 0.79 TLR8 (0.43) NPC1RAB9AHTTGALR3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103168062-B Photovoltaic polymer material, preparation method and application thereof OCEANS KING LIGHTING SCIENCE 2015-04-29 CN disclosed
US-8802812-B2 Photovoltaic polymer material, preparation method and use thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2014-08-12 US disclosed
EP-2660264-A1 PHOTOVOLTAIC POLYMER MATERIAL, PREPARATION METHOD AND USE THEREOF Ocean's King Lighting Science&Technology Co., Ltd. (CN) 2013-11-06 EP disclosed
US-20130267657-A1 PHOTOVOLTAIC POLYMER MATERIAL, PREPARATION METHOD AND USE THEREOF OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2013-10-10 US disclosed
US-8324400-B2 Benzotriazole containing donor-acceptor type polymer as a multi-purpose material TOPPARE LEVENT KAMIL (TR) 2012-12-04 US disclosed
US-20120083583-A1 BENZOTRIAZOLE CONTAINING DONOR-ACCEPTOR TYPE POLYMER AS A MULTI-PURPOSE MATERIAL TOPPARE LEVENT KAMIL (TR) 2012-04-05 US disclosed
WO-2010114497-A1 BENZOTRIAZOLE CONTAINING DONOR-ACCEPTOR TYPE POLYMER AS A MULTI-PURPOSE MATERIAL TOPPARE LEVENT KAMIL (TR) 2010-10-07 WO disclosed
US-20100249367-A1 BENZOTRIAZOLE CONTAINING DONOR-ACCEPTOR TYPE POLYMER AS A MULTI-PURPOSE MATERIAL TOPPARE LEVENT KAMIL 2010-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249367-A1 BENZOTRIAZOLE CONTAINING DONOR-ACCEPTOR TYPE POLYMER AS A MULTI-PURPOSE MATERIAL TYR, AADAT, BHMT2 CSNK2A2 2983/4885CSNK2B 3600/4885CSNK2A1 3653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.