SCHEMBL8916280

SCHEMBL8916280

O=COCCc1ccc(Br)cc1[N+](=O)[O-]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.39
TRPV1 Q8NER1 1/20 0.39
ERN1 O75460 1/20 0.39
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP1A2 P05177 1/20 0.35
RAB9A P51151 2/20 0.34
MAPK1 P28482 2/20 0.34
PKM P14618 1/20 0.34
ACHE P22303 1/20 0.34
CCR5 P51681 1/20 0.34
SNCA P37840 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ABCB1 P08183 1/20 0.33
ABCC1 P33527 1/20 0.33
NPC1 O15118 1/20 0.33
RECQL P46063 1/20 0.33
MEN1 O00255 1/20 0.32
GLA P06280 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702624 0.83 CYP1A2 (0.53) ERN1ALDH1A1TDP1CYP1A2MAPK1
SCHEMBL8912648 0.82 MAPK1 (0.45) ALDH1A1TDP1CYP1A2RAB9AMAPK1
SCHEMBL8916041 0.78 POLB (0.40) ERN1ALDH1A1TDP1CYP1A2SNCA
SCHEMBL11046115 0.78 S100A4 (0.43) S100A4TRPV1ERN1ALDH1A1CYP1A2
SCHEMBL1967927 0.78 ALDH1A1 (0.53) ALDH1A1TDP1RAB9AACHEKDM4E
SCHEMBL7058516 0.77 S100A4 (0.45) S100A4TRPV1ERN1ALDH1A1CYP1A2
SCHEMBL1241995 0.77 ALDH1A1 (0.44) S100A4TRPV1ALDH1A1TDP1CYP1A2
SCHEMBL14756828 0.76 S100A4 (0.44) S100A4TRPV1ERN1ALDH1A1CYP1A2
SCHEMBL4435695 0.76 S100A4 (0.44) S100A4TRPV1ERN1ALDH1A1TDP1
SCHEMBL27577861 0.76 S100A4 (0.44) S100A4TRPV1ERN1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0797580-A2 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS Pfleiderer, Wolfgang (DE) 1997-10-01 EP disclosed
WO-1996018634-A2 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS PFLEIDERER WOLFGANG (DE) 1996-06-20 WO disclosed