Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.59 |
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | HTR2C | P28335 | 8/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 5/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917266 | 0.94 | DRD2 (0.61) | DRD2ACHEHTR2CSLC6A4HTR2A | |
| SCHEMBL8919173 | 0.87 | ACHE (0.58) | DRD2ACHEHTR2CSLC6A4HTR2A | |
| SCHEMBL8916656 | 0.86 | DRD2 (0.58) | DRD2ACHEHTR2CSLC6A4HTR2A | |
| SCHEMBL8917156 | 0.85 | DRD2 (0.58) | DRD2ACHEHTR2CHTR2AHTR1A | |
| SCHEMBL8917307 | 0.85 | DRD2 (0.58) | DRD2ACHEHTR2CSLC6A4HTR2A | |
| SCHEMBL8920261 | 0.85 | DRD2 (0.58) | DRD2ACHEHTR2CSLC6A4HTR2A | |
| SCHEMBL8918516 | 0.85 | DRD2 (0.58) | DRD2ACHEHTR2CSLC6A4HTR2A | |
| SCHEMBL8916842 | 0.85 | DRD2 (0.53) | DRD2ACHEHTR2CSLC6A4HTR2A | |
| SCHEMBL8917040 | 0.83 | ACHE (0.59) | DRD2ACHEHTR2CSLC6A4HTR2A | |
| SCHEMBL8920609 | 0.77 | DRD2 (0.59) | DRD2ACHEHTR2CSLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |