Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.69 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.69 |
| ▸ | NQO2 | P16083 | 6/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567239 | 0.87 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL16130554 | 0.85 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL7955977 | 0.82 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5343123 | 0.82 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5335504 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5341422 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5339853 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5335761 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8886469 | 0.79 | MTNR1A (0.82) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4685402 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686452-A | PROTECTING FROM ENDOTOXIN SHOCK; TREATMENT OF NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |