SCHEMBL8916633

SCHEMBL8916633

CCOC(=O)C(CSc1ccnc(CSc2nc3ccccc3[nH]2)c1C)N1CCOCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.46
NPC1 O15118 4/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP3A4 P08684 1/20 0.46
POLB P06746 2/20 0.41
NOS3 P29474 1/20 0.40
NOS1 P29475 1/20 0.40
NOS2 P35228 1/20 0.40
ALDH1A1 P00352 4/20 0.39
MAPT P10636 3/20 0.39
KDM4E B2RXH2 1/20 0.39
NSD2 O96028 1/20 0.39
ABL1 P00519 1/20 0.39
RIN1 Q13671 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8915219 0.91 RAB9A (0.46) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL8915203 0.87 RAB9A (0.44) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL8916234 0.84 RAB9A (0.54) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL8914165 0.81 RAB9A (0.51) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL8915606 0.79 RAB9A (0.69) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL8915137 0.78 RAB9A (0.44) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL8916879 0.78 RAB9A (0.60) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL8916502 0.77 RAB9A (0.53) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL8916682 0.76 RAB9A (0.42) RAB9ANPC1CYP1A2CYP2D6CYP2C9
SCHEMBL9874235 0.75 RAB9A (0.62) RAB9ANPC1CYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5616581-A BACTERICIDES YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1997-04-01 US disclosed
US-5504082-A BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1996-04-02 US disclosed
EP-0644191-A1 PYRIDINE COMPOUND AND MEDICINAL USE THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1995-03-22 EP disclosed