Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ASH1L | Q9NR48 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915831 | 0.89 | PARP10 (0.50) | SLC22A6ALDH1A1ATMASH1LMEN1 | |
| SCHEMBL8915869 | 0.84 | HTR1B (0.44) | SLC22A6ASH1LMEN1CYP1A2HTR1A | |
| SCHEMBL8914633 | 0.82 | SLC22A6 (0.59) | SLC22A6ALDH1A1ASH1LMEN1CYP1A2 | |
| SCHEMBL8915441 | 0.81 | HTR1D (0.45) | SLC22A6ASH1LMEN1CYP1A2HTR1A | |
| SCHEMBL8917348 | 0.81 | PLG (0.43) | SLC22A6ALDH1A1ASH1LMEN1CYP1A2 | |
| SCHEMBL8915273 | 0.81 | HTR1A (0.45) | SLC22A6ALDH1A1ASH1LMEN1CYP1A2 | |
| SCHEMBL8915816 | 0.81 | PLG (0.43) | SLC22A6ALDH1A1ASH1LMEN1CYP1A2 | |
| SCHEMBL28515587 | 0.79 | SLC22A6 (0.68) | SLC22A6ALDH1A1ATMMEN1CYP1A2 | |
| SCHEMBL8917363 | 0.78 | KMT2A (0.43) | SLC22A6ALDH1A1ASH1LMEN1CYP1A2 | |
| SCHEMBL28842060 | 0.78 | SLC22A6 (0.41) | SLC22A6ASH1LMEN1CYP1A2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703112-A | Method of preventing emesis using tetrahydrobenz CD!indole-6-carbonxamides | ELI LILLY AND COMPANY (US) | 1997-12-30 | — | — | US | disclosed |