Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159213 | 0.87 | ALDH1A1 (0.69) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| SCHEMBL30283 | 0.85 | ALDH1A1 (0.67) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| Water SCHEMBL9512888 | 0.83 | ALDH1A1 (0.65) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| SCHEMBL9592686 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| SCHEMBL4455132 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| SCHEMBL28219066 | 0.82 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| SCHEMBL3413576 | 0.82 | ALDH1A1 (0.73) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| SCHEMBL8166476 | 0.82 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| SCHEMBL10018352 | 0.82 | ALDH1A1 (0.68) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA | |
| SCHEMBL26160 | 0.82 | ALDH1A1 (0.68) | ALDH1A1CYP3A4TDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130567-A | Process for the preparation of aryl dioxolanes | SUN CHEMICAL CORPORATION (US) | 1978-12-19 | — | — | US | claimed |
| CN-101775100-B | Acrylic ester/laminated double hydroxide nanometer composite material and preparation method thereof | CHANGXING CHEMICAL MATERIAL ZHUHAI CO LTD | 2012-05-23 | — | — | CN | disclosed |
| CN-101775100-A | Acrylic ester/laminated double hydroxide nanometer composite material and preparation method thereof | CHANGXING CHEMICAL MATERIAL ZH | 2010-07-14 | — | — | CN | disclosed |
| US-5608065-A | ADAMANTANEOSPIRO-HETEROAROMATIC PYRANS | OPTISCHE WERKE G. RODENSTOCK (DE) | 1997-03-04 | — | — | US | disclosed |
| US-4130567-A | Process for the preparation of aryl dioxolanes | SUN CHEMICAL CORPORATION (US) | 1978-12-19 | — | — | US | disclosed |