Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | NFKBIA | P25963 | 4/20 | 0.46 |
| ▸ | RELA | Q04206 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225130 | 0.72 | MAPK1 (0.53) | MAPK1CA1CA2CA9MEN1 | |
| SCHEMBL29352125 | 0.70 | KMT2A (0.51) | PKMMAPK1CA1CA2CA9 | |
| SCHEMBL4340669 | 0.70 | KMT2A (0.51) | PKMMAPK1CA1CA2CA9 | |
| SCHEMBL6391097 | 0.69 | PDE10A (0.56) | PKMMAPK1CA1CA2CA9 | |
| SCHEMBL13241507 | 0.68 | MAPK1 (0.62) | MAPK1CA1CA2CA9NFKBIA | |
| SCHEMBL7073865 | 0.67 | MAPT (0.61) | MAPK1CA1CA2CA9MEN1 | |
| Potassium Ion SCHEMBL31267534 | 0.67 | MAPK1 (0.66) | PKMMAPK1CA1CA2CA9 | |
| SCHEMBL4108638 | 0.67 | MAPK1 (0.66) | PKMMAPK1CA1CA2CA9 | |
| SCHEMBL7268288 | 0.67 | ALDH1A1 (0.32) | NPSR1ALDH1A1 | |
| SCHEMBL27592567 | 0.66 | MAPK1 (0.70) | MAPK1CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700785-A | ADMINISTERING TO TREAT RETROVIRAL INFECTIONS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0716856-A2 | Therapeutic uses of 2',5'-oligoadenylate derivatives | Temple University of the Commonwealth System of Higher Education (US) | 1996-06-19 | — | — | EP | disclosed |
| EP-0420872-A4 | THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES | — | 1992-10-21 | — | — | EP | disclosed |
| EP-0420872-A1 | THERAPEUTIC USES OF 2',5'-OLIGOADENYLATE DERIVATIVES. | UNIV TEMPLE (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4859768-A | Derivatives of 2', 5'-oligoadenylate and antiviral uses thereof | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1989-08-22 | — | — | US | disclosed |