Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052257 | 1.00 | L3MBTL1 (0.56) | L3MBTL1TSHRMAPK1LMNAALDH1A1 | |
| SCHEMBL8916496 | 1.00 | L3MBTL1 (0.56) | L3MBTL1TSHRMAPK1LMNAALDH1A1 | |
| SCHEMBL8917236 | 1.00 | L3MBTL1 (0.56) | L3MBTL1TSHRMAPK1LMNAALDH1A1 | |
| SCHEMBL8916068 | 1.00 | L3MBTL1 (0.56) | L3MBTL1TSHRMAPK1LMNAALDH1A1 | |
| SCHEMBL8915664 | 0.99 | L3MBTL1 (0.58) | L3MBTL1TSHRMAPK1LMNAALDH1A1 | |
| SCHEMBL8915354 | 0.95 | L3MBTL1 (0.59) | L3MBTL1TSHRMAPK1LMNAALDH1A1 | |
| SCHEMBL8915482 | 0.91 | SMN1; SMN2 (0.62) | L3MBTL1TSHRMAPK1LMNAALDH1A1 | |
| SCHEMBL8918351 | 0.87 | IKBKB (0.65) | L3MBTL1MAPK1LMNAALDH1A1MAPT | |
| SCHEMBL8915350 | 0.87 | IKBKB (0.65) | L3MBTL1MAPK1LMNAALDH1A1MAPT | |
| SCHEMBL8918785 | 0.87 | QPCT (0.58) | MAPK1LMNAALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696140-A | FOR TREATMENT OF ASTHMA, ALLERGIES, NERVOUS SYSTEM DISORDERS OR CANCER | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1997-12-09 | — | — | US | disclosed |