Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 8/20 | 0.34 |
| ▸ | CCND1 | P24385 | 8/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.34 |
| ▸ | CDK7 | P50613 | 8/20 | 0.34 |
| ▸ | CCNH | P51946 | 8/20 | 0.34 |
| ▸ | CDK1 | P06493 | 5/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13154005 | 1.00 | CDK2 (0.38) | CDK2CCNA2CCNA1CDK5DYRK1A | |
| SCHEMBL9272660 | 0.78 | ALDH1A1 (0.48) | ALDH1A1CYP2C19MEN1NPC1RAB9A | |
| SCHEMBL13155604 | 0.77 | KDM4E (0.45) | CDK2CCNA2CCNA1CDK5DYRK1A | |
| SCHEMBL10154754 | 0.73 | IDH1 (0.41) | CDK5ALDH1A1CYP2C19CDK7LMNA | |
| SCHEMBL10125355 | 0.73 | CYP2C19 (0.39) | CDK2CCNA2CCNA1CDK5DYRK1A | |
| SCHEMBL13736558 | 0.73 | IDH1 (0.41) | CDK5ALDH1A1CYP2C19CDK7LMNA | |
| SCHEMBL1268977 | 0.72 | ALDH1A1 (0.39) | CDK2CCNA2CCNA1CDK5DYRK1A | |
| Isaxonine SCHEMBL1270289 | 0.72 | KCNH3 (0.43) | ALDH1A1CYP2C19CDK7LMNAHTT | |
| SCHEMBL24567768 | 0.71 | TLR8 (0.48) | ALDH1A1CYP2C19NPC1 | |
| SCHEMBL30593321 | 0.71 | TLR8 (0.48) | ALDH1A1CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188132-B2 | Linked dibenzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100221214-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221214-A1 | LINKED DIBENZIMIDAZOLE DERIVATIVES | EIF2AK2, NSUN2, ZC3HAV1 | CDK2 130/4885CCNA2 844/4885CCNA1 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.