Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 9/20 | 0.56 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.56 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497520 | 1.00 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL9137670 | 1.00 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8979451 | 0.99 | PLA2G2A (0.54) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8357825 | 0.96 | PLA2G2A (0.59) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8974114 | 0.93 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8004697 | 0.93 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8004701 | 0.93 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL2233038 | 0.91 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL704578 | 0.91 | PLA2G2A (0.52) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL2234605 | 0.91 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5645883-A | Zwitterionic materials | BIOCOMPATIBLES LIMITED (GB) | 1997-07-08 | — | — | US | disclosed |
| EP-0681486-A1 | NEW ZWITTERIONIC MATERIALS | BIOCOMPATIBLES LIMITED (GB) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994016749-A1 | NEW ZWITTERIONIC MATERIALS | BIOCOMPATIBLES LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |