Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.54 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 7/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137670 | 0.99 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8917115 | 0.99 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL497520 | 0.99 | PLA2G2A (0.56) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8357825 | 0.94 | PLA2G2A (0.59) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8004701 | 0.91 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8974114 | 0.91 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL8004697 | 0.91 | PLA2G2A (0.51) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL18912718 | 0.91 | PLA2G2A (0.55) | PLA2G2APLA2G10PLA2G1BPLA2G5KIF11 | |
| SCHEMBL704578 | 0.89 | PLA2G2A (0.52) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 | |
| SCHEMBL2234605 | 0.89 | PLA2G2A (0.49) | PLA2G2APLA2G10PLA2G1BPLA2G5LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710225-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN Biotechnik GmbH (DE) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995032181-A1 | FLUORESCENCE DETERMINATION OF THE ACTIVITY OF LIPOLYTIC ENZYMES | PROGEN BIOTECHNIK GMBH (DE) | 1995-11-30 | — | — | WO | disclosed |