Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.54 |
| ▸ | HPGD | P15428 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916983 | 0.87 | ALDH1A1 (0.46) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL13410042 | 0.80 | GAA (0.47) | ALDH1A1HPGDGAAKDM4EHTT | |
| SCHEMBL6951228 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1HPGDGAAKDM4EHTT | |
| SCHEMBL30587182 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1HPGDGAAKDM4EHTT | |
| SCHEMBL31231118 | 0.77 | GAA (0.56) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL30686655 | 0.77 | GAA (0.56) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL6949718 | 0.77 | GAA (0.56) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL10747419 | 0.74 | GAA (0.44) | ALDH1A1HPGDGAAKDM4EHTT | |
| SCHEMBL13444005 | 0.74 | GAA (0.42) | ALDH1A1HPGDGAAKDM4EHSD17B10 | |
| SCHEMBL8918356 | 0.74 | ALDH1A1 (0.55) | ALDH1A1HPGDGAAKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |