Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.47 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.47 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.47 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746185 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL6137255 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL9452419 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AGAAACHE | |
| SCHEMBL4384277 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL6956520 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL7887160 | 0.80 | MEN1 (0.53) | ALDH1A1MEN1KMT2AACHECACNB4 | |
| SCHEMBL10745416 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL6956135 | 0.79 | SMN1; SMN2 (0.62) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL10747824 | 0.78 | ACHE (0.47) | ALDH1A1MEN1KMT2AHPGDGAA | |
| SCHEMBL8917637 | 0.78 | CACNB4 (0.54) | ALDH1A1KMT2AHPGDGAACACNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |