Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 10/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30090142 | 1.00 | NR3C2 (0.44) | NR3C2MMP12RAB9AMAPTPOLB | |
| SCHEMBL15798567 | 0.84 | POLB (0.39) | NR3C2RAB9AMAPTPOLBALDH1A1 | |
| SCHEMBL8302706 | 0.82 | MMP12 (0.51) | MMP12RAB9AMAPTPOLBALDH1A1 | |
| SCHEMBL4049030 | 0.81 | MMP12 (0.54) | NR3C2MMP12MAPTALDH1A1PARP1 | |
| SCHEMBL23110674 | 0.80 | AKR1B1 (0.48) | MAPTALDH1A1AKR1B1MAPK1SMN1; SMN2 | |
| SCHEMBL30090065 | 0.80 | AKR1B1 (0.48) | MAPTALDH1A1AKR1B1MAPK1SMN1; SMN2 | |
| SCHEMBL8304719 | 0.80 | MMP12 (0.46) | NR3C2MMP12RAB9AMAPTPOLB | |
| SCHEMBL8309098 | 0.80 | PARP1 (0.52) | NR3C2MMP12RAB9AMAPTPOLB | |
| SCHEMBL8307636 | 0.79 | MMP12 (0.51) | MMP12RAB9AMAPTPOLBPARP1 | |
| SCHEMBL10505987 | 0.79 | RAB9A (0.46) | NR3C2MMP12RAB9AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119500034-A | Dynamic tubular reactor and process for preparing flumioxazin | 甘肃联凯生物科技有限公司 | 2025-02-25 | — | — | CN | claimed |
| WO-2014122674-A1 | PROCESS FOR PREPARATION OF DERIVATIVES OF TETRAHYDROPHTHALIMIDE | RALLIS INDIA LIMITED (IN) | 2014-08-14 | — | — | WO | claimed |
| JP-61140571-A | — | — | None | — | — | JP | disclosed |
| CN-119500034-A | Dynamic tubular reactor and process for preparing flumioxazin | 甘肃联凯生物科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-117378617-A | Flumioxazin herbicide and preparation method thereof | 甘肃联凯生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2023247976-A1 | DEUTERATED HERBICIDES BASED ON OXAZINONES AND 6-(TRIFLUOROMETHYL)PYRIMIDINE-2,4-DIONES | REDAG CROP PROTECTION LTD (GB) | 2023-12-28 | — | — | WO | disclosed |
| CN-112480101-B | IRAK4 kinase inhibitor, preparation and application thereof | 中国科学院上海药物研究所 | 2022-11-25 | — | — | CN | disclosed |
| CN-109836393-B | Cyclohexene carboxylate compound and application thereof | 沈阳中化农药化工研发有限公司 | 2022-11-15 | — | — | CN | disclosed |
| US-20220332718-A1 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | GENENTECH, INC. (US) | 2022-10-20 | — | — | US | disclosed |
| US-10988478-B1 | Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators | GENENTECH, INC. (US) | 2021-04-27 | — | — | US | disclosed |
| WO-2021047677-A1 | IRAK4 KINASE INHIBITOR AND PREPARATION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2021-03-18 | — | — | WO | disclosed |
| EP-0263299-B1 | BENZOXAZINES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-11-07 | — | — | EP | disclosed |
| EP-0170191-B1 | TETRAHYDROPHTALIMIDES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4880925-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |
| US-4804394-A | Benzoxazines and use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-02-14 | — | — | US | disclosed |
| US-4792605-A | TETRAHYDROPHTHALIMIDES; HERBICIDES | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1988-12-20 | — | — | US | disclosed |
| EP-0263299-A1 | Benzoxazines | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-04-13 | — | — | EP | disclosed |
| US-4640707-A | Tetrahydrophthalimides and their herbicidal use | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| JP-S61140571-A | NITROBENZOXAZINE DERIVATIVE, AND PREPARATION THEREOF | SUMITOMO CHEM CO LTD | 1986-06-27 | — | — | JP | disclosed |
| EP-0170191-A2 | Tetrahydrophtalimides, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332718-A1 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | IRAK1, IRAK4, IRAK2 | NR3C2 2502/4885MMP12 4115/4885RAB9A 3146/4885 |
| US-10988478-B1 | Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators | IRAK1, IRAK4, IRAK2 | NR3C2 2477/4885MMP12 3773/4885RAB9A 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.