Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12117433 | 0.90 | ABCB1 (0.47) | PTGER4PTGER3PTGER1PTGER2KDM4E | |
| SCHEMBL8406774 | 0.87 | PDCD1 (0.50) | PTGER4PTGER3PTGER1PTGER2GSTP1 | |
| SCHEMBL12117430 | 0.86 | CYP11B1 (0.56) | HTR1ADRD2 | |
| SCHEMBL26185970 | 0.85 | PTGER4 (0.44) | PTGER4PTGER3PTGER1PTGER2GSTP1 | |
| SCHEMBL1758900 | 0.84 | CYP4F2 (0.50) | PTGER4PTGER3PTGER1PTGER2BCHE | |
| SCHEMBL1758960 | 0.81 | PTGER4 (0.44) | PTGER4PTGER3PTGER1PTGER2GSTP1 | |
| SCHEMBL12675701 | 0.81 | SCN8A (0.48) | HTR1ADRD2L3MBTL1SCN8AMAPK1 | |
| SCHEMBL12727690 | 0.81 | HTR1A (0.49) | PTGER4PTGER3PTGER1PTGER2GSTP1 | |
| SCHEMBL31613044 | 0.81 | HTR1A (0.43) | HTR1ASCN8A | |
| SCHEMBL12843213 | 0.79 | BCHE (0.43) | PTGER4PTGER3PTGER1PTGER2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530593-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-20110098431-A1 | Catalyst Compounds and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
| US-5654309-A | KIDNEY, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098431-A1 | Catalyst Compounds and Use Thereof | PAM, AAAS, PAOX | PTGER4 250/4885PTGER3 386/4885PTGER1 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.