SCHEMBL8917420

SCHEMBL8917420

[O]CCC(=O)OCCCCl

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.39
ADRA2A P08913 1/20 0.37
ADRA1A P35348 1/20 0.37
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
HTR2C P28335 1/20 0.35
NAAA Q02083 1/20 0.34
DNM1 Q05193 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918163 0.86
SCHEMBL29226758 0.86 DGKA (0.46) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL7622070 0.86 DGKA (0.41) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL8917428 0.82 DGKA (0.39) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL8919519 0.81
SCHEMBL4958767 0.81 HTR2C (0.46) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL21811737 0.81 DGKA (0.46) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL16342073 0.80 DGKA (0.52) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL3694169 0.79 DGKA (0.50) DGKAADRA2AADRA1AMAPTBLM
SCHEMBL7615124 0.79 NAAA (0.40) DGKAADRA2AADRA1AMAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5620944-A PRE- AND POST-EMERGENT WEED CONTROL NIHON NOHYAKU CO., LTD. (JP) 1997-04-15 US disclosed
EP-0590834-B1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO LTD (JP) 1996-12-11 EP disclosed
EP-0590834-A1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO., LTD. (JP) 1994-04-06 EP disclosed