Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036047 | 0.89 | GAA (0.46) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL430204 | 0.85 | MGAM (0.52) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL17053359 | 0.85 | MGAM (0.43) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL21225193 | 0.85 | MGAM (0.43) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL6265890 | 0.83 | MGAM (0.50) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL1194353 | 0.83 | GAA (0.50) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL8653303 | 0.83 | MGAM (0.50) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL17627159 | 0.82 | MGAM (0.40) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL27703510 | 0.82 | MGAM (0.45) | ALDH1A1TRPA1GAAMGAMSI | |
| SCHEMBL6518852 | 0.82 | MGAM (0.40) | ALDH1A1TRPA1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101003480-B | Ethane 1,1,2 - ethyl ester tricarboxylic acid, preparation method, and application as plasticizer | JINGGANGSHAN COLLEGE | 2010-05-19 | — | — | CN | claimed |
| CN-101003480-A | Ethane 1,1,2 - ethyl ester tricarboxylic acid, preparation method, and application as plasticizer | JINGGANGSHAN COLLEGE (CN) | 2007-07-25 | — | — | CN | claimed |
| CN-112521350-A | Synthetic method of 3-methylamino tetrahydrofuran | 江苏广域化学有限公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-3529301-A1 | FIBER-REINFORCED ORGANIC POLYMER AEROGEL | Blueshift Materials, Inc. (US) | 2019-08-28 | — | — | EP | disclosed |
| EP-3405517-A1 | ORGANIC POLYMER AEROGELS COMPRISING MICROSTRUCTURES | Blueshift Materials, Inc. (US) | 2018-11-28 | — | — | EP | disclosed |
| WO-2018140804-A1 | ORGANIC POLYMER AEROGELS COMPRISING MICROSTRUCTURES | BLUESHIFT INTERNATIONAL MATERIALS, INC. (US) | 2018-08-02 | — | — | WO | disclosed |
| WO-2018078512-A1 | FIBER-REINFORCED ORGANIC POLYMER AEROGEL | BLUESHIFT INTERNATIONAL MATERIALS, INC. (US) | 2018-05-03 | — | — | WO | disclosed |
| CN-105254598-A | Method for synthesizing 3-tetrahydrofurfuryl alcohol | SHIJIAZHUANG XINGBAI BIOENGINEERING CO LTD | 2016-01-20 | — | — | CN | disclosed |
| CN-104961710-A | Synthesis method of dinotefuran | SHANDONG ACADEMY OF PESTICIDE SCIENCES | 2015-10-07 | — | — | CN | disclosed |
| US-8110577-B2 | Histone deacetylase inhibitors | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2012-02-07 | — | — | US | disclosed |
| US-20100160392-A1 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2010-06-24 | — | — | US | disclosed |
| CN-101003480-B | Ethane 1,1,2 - ethyl ester tricarboxylic acid, preparation method, and application as plasticizer | JINGGANGSHAN COLLEGE | 2010-05-19 | — | — | CN | disclosed |
| CN-101003480-B | Ethane 1,1,2 - ethyl ester tricarboxylic acid, preparation method, and application as plasticizer | JINGGANGSHAN COLLEGE | 2010-05-19 | — | — | CN | disclosed |
| CN-101003480-A | Ethane 1,1,2 - ethyl ester tricarboxylic acid, preparation method, and application as plasticizer | JINGGANGSHAN COLLEGE (CN) | 2007-07-25 | — | — | CN | disclosed |
| CN-101003480-A | Ethane 1,1,2 - ethyl ester tricarboxylic acid, preparation method, and application as plasticizer | JINGGANGSHAN COLLEGE (CN) | 2007-07-25 | — | — | CN | disclosed |
| US-5658935-A | USEFUL AS INHIBITORS OF THROMBOCYTE AGGREGATION, THE METASTASIS OF CARCINOMA CELLS AND THE BINDING OF OSTEOCLASTS ON BONE SURFACES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160392-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC4 | ALDH1A1 2757/4885TRPA1 4225/4885GAA 3800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.