SCHEMBL430204

SCHEMBL430204

CCOC(=O)CC(C(=O)OCC)C(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.52
GAA P10253 1/20 0.52
SI P14410 1/20 0.52
MGAM2 Q2M2H8 1/20 0.52
ALDH1A1 P00352 6/20 0.48
TRPA1 O75762 1/20 0.48
ALOX15 P16050 3/20 0.47
CYP3A4 P08684 2/20 0.47
TSHR P16473 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HSD17B10 Q99714 2/20 0.46
CHRM1 P11229 1/20 0.46
ADORA1 P30542 1/20 0.46
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP2D6 P10635 1/20 0.41
SOAT1 P35610 1/20 0.40
KMT2A Q03164 3/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460011 0.89 MGAM (0.46) MGAMGAASIMGAM2ALDH1A1
SCHEMBL19105326 0.87 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL4661806 0.87 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL11565070 0.87 ALOX15 (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL4529653 0.87 MGAM (0.44) MGAMGAASIMGAM2ALDH1A1
SCHEMBL19105350 0.86 GAA (0.54) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8917503 0.85 ALDH1A1 (0.54) MGAMGAASIMGAM2ALDH1A1
SCHEMBL25181738 0.85 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL6974108 0.85 MGAM (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL10843736 0.83 GAA (0.41) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239042-A9 IN-SITU REACTIVE CURING AND INFILTRATION IN BINDER JET ADDITIVE MANUFACTURING U. S. DEPARTMENT OF ENERGY 2024-07-18 US claimed
US-20240017484-A1 IN-SITU REACTIVE CURING AND INFILTRATION IN BINDER JET ADDITIVE MANUFACTURING UT BATTELLE LLC (US) 2024-01-18 US claimed
US-10087383-B2 Aviation fuel additive scavenger AFTON CHEMICAL CORPORATION (US) 2018-10-02 US claimed
US-20170283728-A1 AVIATION FUEL ADDITIVE SCAVENGER AFTON CHEMICAL CORPORATION 2017-10-05 US claimed
EP-3225681-A1 AVIATION FUEL ADDITIVE SCAVENGER Afton Chemical Corporation (US) 2017-10-04 EP claimed
US-5795447-A Separation of 2-butanol from isobutanol by extractive distillation BERG LLOYD (US) 1998-08-18 US claimed
EP-4013749-B1 ALKYNYL QUINAZOLINE COMPOUNDS BLACK DIAMOND THERAPEUTICS INC (US) 2026-03-11 EP disclosed
US-12565000-B2 In-situ reactive curing and infiltration in binder jet additive manufacturing UT-BATTELLE, LLC (US) 2026-03-03 US disclosed
US-20260049063-A1 ALKYNYL QUINAZOLINE COMPOUNDS BLACK DIAMOND THERAPEUTICS INC (US) 2026-02-19 US disclosed
US-20260001838-A1 NANOMATERIALS GUIDE THERAPEUTICS LLC (US) 2026-01-01 US disclosed
US-12448492-B2 Organic polymer aerogels comprising microstructures Blueshift Materials, Inc. (US) 2025-10-21 US disclosed
US-12435035-B2 Nanomaterials GUIDE THERAPEUTICS, LLC (US) 2025-10-07 US disclosed
US-12435046-B2 Alkynyl quinazoline compounds BLACK DIAMOND THERAPEUTICS, INC. (US) 2025-10-07 US disclosed
US-4143160-A COSMETIC CONTAINING POLYCARBOXYLIC ACIDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-03-06 US disclosed
US-4142046-A BACTERICIDES, 7-AMINO-CEPHALOSPORINS SMITHKLINE CORPORATION (US) 1979-02-27 US disclosed
US-4076601-A FROM DIMETHYL MALONATE MONSANTO COMPANY (US) 1978-02-28 US disclosed
US-4060610-A Pharmaceutical compositions comprising 7-acyl-3-(substituted triazolyl thiomethyl)-cephalosporins and methods of treating bacterial infections SMITHKLINE CORPORATION (US) 1977-11-29 US disclosed
US-3989694-A ANTIBACTERIAL SMITHKLINE CORPORATION (US) 1976-11-02 US disclosed
US-3974165-A Hypotensive agents BRISTOL-MYERS COMPANY (US) 1976-08-10 US disclosed
US-3959263-A Prostaglandin intermediate AMERICAN HOME PRODUCTS CORPORATION (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435046-B2 Alkynyl quinazoline compounds GLS, GLS2, MCL1 MGAM 4821/4885GAA 330/4885SI 1752/4885
US-20260001838-A1 NANOMATERIALS SLC10A1, NPC1L1, FABP1 MGAM 4788/4885GAA 3451/4885SI 3661/4885
US-12435035-B2 Nanomaterials NPC1, NPC1L1, FABP1 MGAM 4599/4885GAA 1479/4885SI 3839/4885
US-12565000-B2 In-situ reactive curing and infiltration in binder jet additive manufacturing BHMT, TST, TMT1A MGAM 693/4885GAA 4296/4885SI 1844/4885
US-20260049063-A1 ALKYNYL QUINAZOLINE COMPOUNDS H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MCL1, BCL6 MGAM 4777/4885GAA 719/4885SI 2042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.