SCHEMBL8917831

SCHEMBL8917831

OC=CCc1ccc2[nH]nnc2c1-c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.30
AKT2 P31751 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5616785 0.83 CHEK1 (0.32) CHEK1AKT2
SCHEMBL5321435 0.81 CHEK1 (0.34) CHEK1AKT2
SCHEMBL27428105 0.79 DPP4 (0.41) CHEK1AKT2
SCHEMBL15766083 0.78
SCHEMBL3744873 0.77 SMN1; SMN2 (0.37) CHEK1AKT2
SCHEMBL1395526 0.77
SCHEMBL28235005 0.76 AKT2 (0.36) CHEK1AKT2
SCHEMBL28723534 0.75 AKT2 (0.35) CHEK1AKT2
SCHEMBL9616136 0.74
SCHEMBL1938294 0.74 HSD11B1 (0.38) CHEK1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1098677-A None JP disclosed
CN-101035848-B Ultraviolet (UV) absorbing compounds and compositions containing UV absorbing compounds MILLIKEN & CO 2010-12-29 CN disclosed
CN-101035848-A Ultraviolet (UV) absorbing compounds and compositions containing UV absorbing compounds MILLIKEN & CO (US) 2007-09-12 CN disclosed
US-5624982-A BENZOTRIAZOLE COMPOUNDS FOR LIGHT STABILIZERS OF TETRAMETHYL PIPERIDINYL SEBACATE FOR STYRENE POLYMERS BAYER ANTWERPEN SA/NV (BE) 1997-04-29 US disclosed
EP-0736064-A1 STABILIZER SYSTEM FOR NON YELLOWING POLYMER COMPOSITION BAYER ANTWERPEN N.V. (BE) 1996-10-09 EP disclosed
US-5492948-A STABILIZER FOR STYRENE POLYMERS CONSISTING OF A BENZOTRIAZOLE, OLIGOMERIC CONDENSATE OF 2,4-DICHLORO-6-MORPHOLINO-S-TRIAZINE AND N,N*-/2,2,6,6-TETRAMETHYLPIPERIDYL/HEXAMETHYLENEDIAMINE, TRIS/3,5-DI-TERT-BUTYL-4-HYDROXYBENZYL/ ISOCYANURATE MONSANTO COMPANY (US) 1996-02-20 US disclosed
WO-1995015358-A1 STABILIZER SYSTEM FOR NON YELLOWING POLYMER COMPOSITION BAYER ANTWERPEN SA/NV (BE) 1995-06-08 WO disclosed
JP-H0198677-A ADHESIVE RESIN COMPOSITION AND LAMINATE THEREOF ON METAL SHOWA DENKO KK 1989-04-17 JP disclosed