Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794958 | 0.84 | MAPK14 (0.36) | SMN1; SMN2GSK3B | |
| SCHEMBL5321435 | 0.83 | CHEK1 (0.34) | SMN1; SMN2NPC1HPGDRAB9AMEN1 | |
| SCHEMBL27428105 | 0.83 | DPP4 (0.41) | CDK1GSK3AGSK3BMEN1KMT2A | |
| SCHEMBL28235005 | 0.81 | AKT2 (0.36) | TSHRKMT2ACHEK1AKT2KDM4E | |
| SCHEMBL9952233 | 0.80 | PAX8 (0.43) | PAX8ALOX5BCL2BCL2L1 | |
| SCHEMBL5616785 | 0.79 | CHEK1 (0.32) | NPC1HPGDRAB9AKMT2ACHEK1 | |
| SCHEMBL28723534 | 0.79 | AKT2 (0.35) | SMN1; SMN2HPGDKMT2ACHEK1AKT2 | |
| SCHEMBL1938294 | 0.78 | HSD11B1 (0.38) | TSHRCHEK1AKT2KDM4E | |
| SCHEMBL30933259 | 0.78 | CYP3A4 (0.43) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18393343 | 0.78 | CYP3A4 (0.43) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816424-B2 | Biodegradable plastics composition, molded article of the composition, and method of controlling biodegradation rate | NISSHINBO INDUSTRIES, INC. (JP) | 2010-10-19 | — | — | US | disclosed |