Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 2/20 | 0.52 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917299 | 0.93 | DRD2 (0.56) | DRD2HTR1AHTR2AADRA2AHTR2C | |
| SCHEMBL8917984 | 0.89 | HTR2A (0.55) | DRD2HTR1AHTR2AADRA2AHTR2C | |
| Hydrochloric Acid SCHEMBL8991836 | 0.88 | HTR2A (0.55) | DRD2HTR1AHTR2AADRA2AHTR2C | |
| SCHEMBL9408142 | 0.87 | DRD2 (0.56) | DRD2HTR2AKCNH2SLC6A4ACHE | |
| SCHEMBL8918296 | 0.87 | MCHR1 (0.62) | DRD2HTR1AHTR2AADRA2AHTR2C | |
| Hydrochloric Acid SCHEMBL8917151 | 0.84 | MCHR1 (0.54) | DRD2HTR1AHTR2AADRA2AHTR2C | |
| SCHEMBL8917275 | 0.83 | DRD2 (0.51) | DRD2HTR1AHTR2AADRA2AHTR2C | |
| SCHEMBL8916687 | 0.83 | DRD2 (0.54) | DRD2HTR1AHTR2AADRA2AHTR2C | |
| Hydrochloric Acid SCHEMBL8991890 | 0.82 | MCHR1 (0.56) | DRD2HTR1AHTR2AADRA2AHTR2C | |
| SCHEMBL8916147 | 0.81 | DRD2 (0.54) | DRD2HTR1AHTR2AADRA2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |