Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | FABP3 | P05413 | 1/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222758 | 0.93 | RXRA (0.58) | RXRARXRBRXRGTDP1EGLN1 | |
| SCHEMBL417159 | 0.88 | KAT6A (0.61) | TDP1L3MBTL1LMNAMAPK1HTT | |
| SCHEMBL17799599 | 0.87 | KAT6A (0.63) | TDP1L3MBTL1LMNAMAPK1HTT | |
| Methyl Alcohol SCHEMBL28372647 | 0.85 | ALDH1A1 (0.55) | TDP1L3MBTL1FABP3KDM4EALDH1A1 | |
| SCHEMBL294721 | 0.84 | ALDH1A1 (0.58) | L3MBTL1FABP3KDM4EALDH1A1LMNA | |
| SCHEMBL30136447 | 0.84 | ALDH1A1 (0.58) | L3MBTL1FABP3KDM4EALDH1A1LMNA | |
| SCHEMBL3647093 | 0.84 | EGLN1 (0.52) | TDP1EGLN1KDM4EALDH1A1HPGD | |
| SCHEMBL5924712 | 0.84 | EGLN1 (0.52) | TDP1EGLN1KDM4EALDH1A1HPGD | |
| SCHEMBL27847027 | 0.84 | ATM (0.56) | TDP1L3MBTL1EGLN1KDM4EALDH1A1 | |
| SCHEMBL30017788 | 0.82 | ALDH1A1 (0.56) | L3MBTL1FABP3KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644416-A | LIQUID CRYSTAL POLYMER FILM | FUJI XEROX CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0395006-B1 | Display composition, coloring pigment, and recording material | SONY CORP (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5179065-A | Recording material with a display composition including a coloring pigment | SONY CORPORATION (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5160371-A | Leuco dye and quaternized clay | SONY CORPORATION (JP) | 1992-11-03 | — | — | US | disclosed |
| EP-0294724-B1 | DISPLAY MATERIAL | SONY CORPORATION (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-4957352-A | Electrochromic display device | SONY CORPORATION (JP) | 1990-09-18 | — | — | US | disclosed |
| US-4940689-A | Display material | SONY CORPORATION (JP) | 1990-07-10 | — | — | US | disclosed |
| EP-0301513-A2 | Electrochromic display | SONY CORPORATION (JP) | 1989-02-01 | — | — | EP | disclosed |
| EP-0294724-A2 | Display material | SONY CORPORATION (JP) | 1988-12-14 | — | — | EP | disclosed |