Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BPTF | Q12830 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917688 | 0.94 | MAPT (0.37) | MAPTTP53MEN1KMT2AHTR3A | |
| SCHEMBL8916688 | 0.91 | MAPT (0.37) | MAPTTP53MEN1KMT2AHTR3A | |
| SCHEMBL8918059 | 0.87 | MAPT (0.37) | MAPTTP53MEN1KMT2AHTR3A | |
| SCHEMBL8916768 | 0.86 | CTSS (0.40) | MAPTTP53MEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL8917167 | 0.85 | CTSS (0.40) | MAPTTP53MEN1KMT2APOLB | |
| SCHEMBL8915765 | 0.85 | MAPT (0.38) | MAPTTP53MEN1KMT2AHTR3A | |
| SCHEMBL8915761 | 0.84 | MAPT (0.39) | MAPTTP53HTR3ABRD3POLB | |
| SCHEMBL8920013 | 0.84 | TP53 (0.39) | MAPTTP53HTR3ABRD3POLB | |
| SCHEMBL8916455 | 0.83 | MAPT (0.44) | MAPTTP53MEN1KMT2APOLB | |
| SCHEMBL8916431 | 0.82 | TP53 (0.38) | MAPTTP53HTR3ABRD3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |