Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 11/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 10/20 | 0.37 |
| ▸ | DRD3 | P35462 | 10/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8917167 | 0.99 | CTSS (0.40) | CTSSDRD2SLC6A4TP53MAPT | |
| SCHEMBL8916989 | 0.94 | DRD2 (0.38) | CTSSDRD2SLC6A4TP53MAPT | |
| Hydrochloric Acid SCHEMBL8916342 | 0.93 | DRD2 (0.38) | CTSSDRD2SLC6A4TP53MAPT | |
| SCHEMBL8917881 | 0.92 | CTSS (0.40) | CTSSDRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8916164 | 0.92 | CTSS (0.48) | CTSSDRD2SLC6A4TP53MAPT | |
| Hydrochloric Acid SCHEMBL8918060 | 0.91 | CTSS (0.48) | CTSSDRD2SLC6A4TP53MAPT | |
| SCHEMBL8916977 | 0.91 | CTSS (0.37) | CTSSDRD2SLC6A4TP53MAPT | |
| SCHEMBL8920505 | 0.90 | CTSS (0.39) | CTSSDRD2SLC6A4TP53MAPT | |
| SCHEMBL8919111 | 0.90 | DRD2 (0.51) | DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8917007 | 0.87 | CTSS (0.46) | CTSSDRD2SLC6A4HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |