Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917931 | 1.00 | ADRA1D (0.31) | ADRA1DHTR1AADRA1BADRA1A | |
| SCHEMBL8917599 | 0.89 | — | — | |
| SCHEMBL9525010 | 0.88 | SLC5A2 (0.30) | — | |
| SCHEMBL8916677 | 0.86 | KDM4E (0.31) | — | |
| SCHEMBL8916664 | 0.86 | KDM4E (0.31) | — | |
| SCHEMBL9524889 | 0.79 | ADRA1D (0.42) | ADRA1DHTR1AADRA1BADRA1A | |
| SCHEMBL7502807 | 0.79 | ADRA1D (0.42) | ADRA1DHTR1AADRA1BADRA1A | |
| SCHEMBL9523947 | 0.77 | — | — | |
| SCHEMBL9525256 | 0.77 | GCGR (0.33) | — | |
| SCHEMBL8874773 | 0.76 | RARB (0.36) | ADRA1DHTR1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5651918-A | Optically active 1,3-dioxolane derivatives carrying a mesogenic radical in the 4-position, a process for their preparation and their use as doping agents in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| US-5348684-A | Organosilylalkyl or organosilylalkenyl compounds, process for preparing them and their use in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-20 | — | — | US | disclosed |