Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | F3 | P13726 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688426 | 0.84 | ALDH1A1 (0.41) | HSD17B10ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2688423 | 0.84 | ALDH1A1 (0.41) | HSD17B10ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2688427 | 0.84 | ALDH1A1 (0.41) | HSD17B10ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9972607 | 0.83 | HSD17B10 (0.37) | HSD17B10SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL3046635 | 0.82 | FKBP1A (0.45) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL3046636 | 0.82 | FKBP1A (0.45) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL9972620 | 0.82 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL3045671 | 0.81 | FKBP1A (0.45) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL3045668 | 0.81 | FKBP1A (0.45) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL12021080 | 0.81 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686565-A | ANTIINFLAMMATORY AGENTS | SCIOS INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5552383-A | ANALGESIC, ANTIINFLAMMATORY FOR WOUNDS | SCIOS NOVA INC. (US) | 1996-09-03 | — | — | US | disclosed |