Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.69 |
| ▸ | MMP2 | P08253 | 5/20 | 0.69 |
| ▸ | MMP9 | P14780 | 5/20 | 0.69 |
| ▸ | EGFR | P00533 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918070 | 1.00 | MMP1 (0.69) | MMP1MMP2MMP9EGFRMAPT | |
| N-O-Tolylcinnamamide SCHEMBL29844171 | 0.82 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL10492396 | 0.82 | MMP1 (0.77) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL10492394 | 0.82 | MMP1 (0.77) | MMP1MMP2MMP9EGFRMAPT | |
| N-O-Tolylcinnamamide SCHEMBL15902545 | 0.82 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| N-O-Tolylcinnamamide SCHEMBL2593754 | 0.82 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| N-O-Tolylcinnamamide SCHEMBL2593756 | 0.82 | MMP1 (1.00) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL9093972 | 0.81 | SMN1; SMN2 (0.69) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL9093967 | 0.81 | SMN1; SMN2 (0.69) | MMP1MMP2MMP9EGFRMAPT | |
| SCHEMBL8059572 | 0.81 | LTB4R (0.85) | MMP1MMP2MMP9EGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |