Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 7/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916632 | 0.92 | DRD2 (0.54) | DRD2SLC6A4HTR2AHTR7ACHE | |
| SCHEMBL8917237 | 0.91 | DRD2 (0.53) | DRD2SLC6A4HTR2AHTR7ACHE | |
| SCHEMBL8918089 | 0.90 | DRD2 (0.54) | DRD2SLC6A4HTR2AHTR7ACHE | |
| SCHEMBL8920271 | 0.90 | DRD2 (0.56) | DRD2SLC6A4HTR2AHTR7ACHE | |
| SCHEMBL8918706 | 0.88 | DRD2 (0.56) | DRD2SLC6A4HTR2AHTR7ACHE | |
| SCHEMBL8916147 | 0.88 | DRD2 (0.54) | DRD2SLC6A4HTR2AHTR7ACHE | |
| Oxalic Acid SCHEMBL8917876 | 0.86 | HTR2A (0.51) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| Fumaric Acid SCHEMBL8991885 | 0.86 | DRD2 (0.51) | DRD2SLC6A4HTR2AHTR7ACHE | |
| Fumaric Acid SCHEMBL8991884 | 0.86 | DRD2 (0.51) | DRD2SLC6A4HTR2AHTR7ACHE | |
| SCHEMBL8917101 | 0.86 | DRD2 (0.54) | DRD2SLC6A4HTR2AHTR7ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |