Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29013806 | 0.92 | CA1 (0.41) | MAPTNPSR1MAPK1TDP1KDM4E | |
| SCHEMBL29725078 | 0.90 | MAPT (0.49) | MAPTNPSR1MAPK1TDP1KDM4E | |
| SCHEMBL616838 | 0.90 | MAPT (0.49) | MAPTNPSR1MAPK1TDP1KDM4E | |
| SCHEMBL30240950 | 0.90 | MAPT (0.49) | MAPTNPSR1MAPK1TDP1KDM4E | |
| SCHEMBL5859406 | 0.90 | MAPT (0.49) | MAPTNPSR1MAPK1TDP1KDM4E | |
| SCHEMBL28144789 | 0.90 | PTPN11 (0.46) | MAPTNPSR1MAPK1TDP1KDM4E | |
| SCHEMBL17993725 | 0.88 | MAPT (0.47) | MAPTNPSR1MAPK1TDP1KDM4E | |
| SCHEMBL27860728 | 0.87 | PTPN11 (0.44) | MAPTKDM4ELMNAGAAMAPK10 | |
| SCHEMBL27778872 | 0.87 | LMNA (0.44) | MAPTNPSR1MAPK1TDP1KDM4E | |
| SCHEMBL8380968 | 0.87 | MEN1 (0.45) | MAPTNPSR1MAPK1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679794-A | ACTINIC LIGHT RESISTANCE, PROCESSING HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |