SCHEMBL8380968

SCHEMBL8380968

OCCOc1ccc(-c2ncnc(-c3ccc(Br)cc3)n2)c(O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.45
KMT2A Q03164 7/20 0.45
MAPT P10636 5/20 0.45
LMNA P02545 4/20 0.45
NPSR1 Q6W5P4 2/20 0.45
MAPK1 P28482 2/20 0.45
KDM4E B2RXH2 1/20 0.41
HTT P42858 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.37
ALDH2 P05091 2/20 0.37
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
BLM P54132 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
DHPS P49366 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580702 0.91 MEN1 (0.47) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL29356875 0.91 MEN1 (0.47) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL29013806 0.89 CA1 (0.41) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL4980859 0.87 LMNA (0.49) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL8379513 0.87 KMT2A (0.48) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL8918210 0.87 MAPT (0.46) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL4977185 0.82 L3MBTL1 (0.43) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL4978800 0.82 NPC1 (0.46) MEN1KMT2AMAPTLMNANPSR1
SCHEMBL1243172 0.82 NPC1 (0.47) MEN1KMT2AMAPTLMNAKDM4E
SCHEMBL28859654 0.79 NPC1 (0.44) MEN1KMT2AMAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117999312-A Fluoropolymer-free polymer processing aid 诺瓦化学品(国际)股份有限公司 2024-05-07 CN disclosed
CN-117693543-A Block copolymer polymer processing aids 诺瓦化学品(国际)股份有限公司 2024-03-12 CN disclosed
CN-114867776-A Coated aramid pulp for rubber reinforcement 巴斯夫欧洲公司 2022-08-05 CN disclosed
US-5942626-A REACTING A 5-HALO-SUBSTITUTED BENZOTRIAZOLE WITH A MERCAPTO COMPOUND IN THE PRESENCE OF A GROUP 1A METAL OR GROUP 2A COMPOUND FORMING 5-THIO-SUBSTITUTED 2H-BENZOTRIAZOLES HAVING ENHANCED ABSORBANCE AT LONGER WAVELENGTHS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-24 US disclosed
US-5849821-A Tris-aryl-s-triazines substituted with biphenylyl groups CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-12-15 US disclosed
US-5844025-A 1,2-Bis-adducts of stable nitroxides with substituted ethylenes and stabilized compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-12-01 US disclosed
US-5844026-A N,N',N''-tris{2,4-bis Hydrocarbyloxy-2,2,6,6-tetra-methylpiperidin-4-yl)alkylamino!-s-triazin-6-yl}-3,3'-ethylenediiminodipropylamines, their isomers and bridged derivatives and polymer compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-12-01 US disclosed
US-5726309-A ULTRAVIOLET RADIATION ABSORBERS; THERMAL STABILIZERS FOR POLYMER SUBSTRATES, ESPECIALLY AUTOMOTIVE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-03-10 US disclosed
US-5684070-A FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-11-04 US disclosed
US-5681955-A PHOTOSTABILITY OF POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-10-28 US disclosed
US-5679794-A ACTINIC LIGHT RESISTANCE, PROCESSING HEAT RESISTANCE CIBA-GEIGY CORPORATION (US) 1997-10-21 US disclosed
US-5675004-A POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS CIBA-GEIGY CORPORATION (US) 1997-10-07 US disclosed
US-5512621-A STABILIZER FOR POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1996-04-30 US disclosed