Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536535 | 0.93 | MAPT (0.55) | MAPTS1PR4MRGPRX4HPGDTSHR | |
| SCHEMBL3453883 | 0.87 | S1PR4 (0.54) | MAPTS1PR4MRGPRX4HPGDTSHR | |
| SCHEMBL8917491 | 0.86 | ALDH1A1 (0.54) | MAPTMRGPRX4HPGDTSHRRAB9A | |
| Hydrochloric Acid SCHEMBL21595895 | 0.85 | S1PR4 (0.53) | MAPTS1PR4MRGPRX4HPGDSMN1; SMN2 | |
| SCHEMBL9214093 | 0.83 | MAPT (0.57) | MAPTS1PR4HPGDTSHRRAB9A | |
| SCHEMBL11413525 | 0.82 | S1PR4 (0.66) | MAPTS1PR4TDP1 | |
| SCHEMBL15894082 | 0.82 | ALDH1A1 (0.60) | MAPTS1PR4HPGDTSHRRAB9A | |
| SCHEMBL8955798 | 0.82 | MAPK1 (0.61) | MAPTS1PR4MRGPRX4HPGDTSHR | |
| SCHEMBL15894081 | 0.82 | ALDH1A1 (0.60) | MAPTS1PR4HPGDTSHRRAB9A | |
| SCHEMBL8778533 | 0.82 | MAPT (0.53) | MAPTS1PR4HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696140-A | FOR TREATMENT OF ASTHMA, ALLERGIES, NERVOUS SYSTEM DISORDERS OR CANCER | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1997-12-09 | — | — | US | disclosed |