Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727219 | 0.98 | MAPK1 (0.62) | MAPK1TP53L3MBTL1S1PR4MAPT | |
| SCHEMBL8794130 | 0.93 | TP53 (0.64) | MAPK1TP53L3MBTL1S1PR4MAPT | |
| SCHEMBL8955786 | 0.87 | ALDH1A1 (0.69) | MAPK1TP53L3MBTL1S1PR4MAPT | |
| SCHEMBL4334537 | 0.87 | S1PR4 (0.61) | MAPK1TP53L3MBTL1S1PR4MAPT | |
| SCHEMBL9214093 | 0.83 | MAPT (0.57) | MAPK1TP53L3MBTL1S1PR4MAPT | |
| SCHEMBL11413525 | 0.82 | S1PR4 (0.66) | S1PR4MAPTTDP1 | |
| SCHEMBL15894081 | 0.82 | ALDH1A1 (0.60) | MAPK1TP53L3MBTL1S1PR4MAPT | |
| SCHEMBL8918360 | 0.82 | MAPT (0.53) | MAPK1S1PR4MAPTALDH1A1TDP1 | |
| SCHEMBL15894082 | 0.82 | ALDH1A1 (0.60) | MAPK1TP53L3MBTL1S1PR4MAPT | |
| SCHEMBL8778533 | 0.82 | MAPT (0.53) | MAPK1S1PR4MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |