SCHEMBL8918549

SCHEMBL8918549

CCOC(COC(=O)CC[O])OC

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
ENPP2 Q13822 8/20 0.35
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LPAR6 P43657 3/20 0.34
LPAR1 Q92633 3/20 0.34
LPAR4 Q99677 3/20 0.34
LPAR5 Q9H1C0 3/20 0.34
LPAR2 Q9HBW0 3/20 0.34
LPAR3 Q9UBY5 3/20 0.34
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918315 0.91 MAPT (0.38) MAPTENPP2LMNAALDH1A1CYP3A4
SCHEMBL8641999 0.87 MAPT (0.47) MAPTENPP2LMNAALDH1A1CYP3A4
SCHEMBL4854694 0.84 MAPT (0.34) MAPTENPP2LMNAALDH1A1CYP3A4
SCHEMBL297785 0.81 MAPT (0.41) MAPTLMNAALDH1A1CYP3A4TSHR
SCHEMBL4856239 0.80 MGAM (0.31)
SCHEMBL9748310 0.79 ALDH1A1 (0.44) LMNAALDH1A1
SCHEMBL1842052 0.77 ALDH1A1 (0.44) MAPTENPP2LMNAALDH1A1CYP3A4
SCHEMBL522535 0.77 MAPT (0.52) MAPTENPP2LMNAALDH1A1CYP3A4
SCHEMBL10923832 0.77 MAPT (0.47) MAPTENPP2LMNAALDH1A1CYP3A4
SCHEMBL26300306 0.77 ALDH1A1 (0.46) MAPTLMNAALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5620944-A PRE- AND POST-EMERGENT WEED CONTROL NIHON NOHYAKU CO., LTD. (JP) 1997-04-15 US disclosed
EP-0590834-B1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO LTD (JP) 1996-12-11 EP disclosed
EP-0590834-A1 Phenylimidazole derivatives, processes for production thereof, herbicides comprising said derivatives, and usages of said herbicides NIHON NOHYAKU CO., LTD. (JP) 1994-04-06 EP disclosed