Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848161 | 0.90 | MGAM (0.34) | MGAMGAASIMGAM2 | |
| SCHEMBL4854694 | 0.86 | MAPT (0.34) | — | |
| SCHEMBL8641999 | 0.81 | MAPT (0.47) | — | |
| SCHEMBL9748310 | 0.80 | ALDH1A1 (0.44) | MGAMGAASIMGAM2 | |
| SCHEMBL8918549 | 0.80 | MAPT (0.35) | — | |
| SCHEMBL8894699 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL26300306 | 0.79 | ALDH1A1 (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL11544393 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL1397463 | 0.76 | TSHR (0.53) | MGAMGAASIMGAM2 | |
| SCHEMBL2332613 | 0.76 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329694-B2 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2008-02-12 | — | — | US | disclosed |
| EP-1445641-B1 | OCULAR LENS | JOHNSON & JOHNSON VISION CARE (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20040201820-A1 | Ocular lens | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-14 | — | — | US | disclosed |
| US-20040198938-A1 | Monomers, polymers and ophthalmic lenses | JOHNSON & JOHNSON VISION CARE, INC. | 2004-10-07 | — | — | US | disclosed |
| EP-1445641-A1 | OCULAR LENS | Johnson & Johnson Vision Care, Inc. (US) | 2004-08-11 | — | — | EP | disclosed |
| EP-1424339-A1 | MONOMERS, POLYMERS AND OPHTHALMIC LENSES | Johson & Johnson Vision Care Inc. (US) | 2004-06-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198938-A1 | Monomers, polymers and ophthalmic lenses | LOXL1, CRYAA, UACA | MGAM 1176/4885GAA 3218/4885SI 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.