Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 3/20 | 0.44 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919032 | 0.77 | KDM4E (0.51) | HDAC1HDAC6KMT2AMAPTCYP1A2 | |
| SCHEMBL8919568 | 0.76 | HDAC1 (0.48) | HDAC1HDAC6KMT2AMEN1KDM4E | |
| SCHEMBL8919561 | 0.76 | HDAC1 (0.48) | HDAC1HDAC6KMT2AMEN1KDM4E | |
| SCHEMBL8920234 | 0.75 | THRB (0.54) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL8921545 | 0.75 | THRB (0.54) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL8921547 | 0.75 | THRB (0.54) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL10242977 | 0.74 | HDAC3 (0.61) | HDAC3HDAC1HDAC2MGAMHPGDS | |
| SCHEMBL13113540 | 0.74 | MGAM (0.56) | HDAC3HDAC1HDAC2MGAMKMT2A | |
| SCHEMBL8919987 | 0.74 | SMN1; SMN2 (0.55) | HDAC3HDAC1HDAC2KMT2ACYP1A2 | |
| SCHEMBL7209315 | 0.73 | MGAM (0.59) | HDAC3HDAC1HDAC2MGAMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691366-A | UNSATURATED NITRO OXIME FORMED BY REACTION OF DINITROGEN TRIOXIDE WITH DIOLEFIN ETHER, SULFIDE OR AMINE TO BE USED AS VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |