Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.45 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639251 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL8638318 | 0.72 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL6350778 | 0.72 | PTGS2 (0.61) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL6345546 | 0.72 | PTGS2 (0.83) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL8765808 | 0.66 | PTGS2 (0.62) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL8609145 | 0.65 | PTGS2 (0.65) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL8765747 | 0.65 | PTGS2 (0.60) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL8637420 | 0.65 | PTGS2 (0.60) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL8635532 | 0.65 | PTGS2 (0.68) | PTGS2PTGS1CA2CA1CA9 | |
| SCHEMBL6621421 | 0.64 | PTGS2 (0.50) | PTGS2PTGS1CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639777-A | 1,4,5-triphenyl pyrazolyl compounds for the treatment of inflammation and inflammation-related disorders | G.D. SEARLE & CO. (US) | 1997-06-17 | — | — | US | claimed |