Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13924514 | 1.00 | TSHR (0.54) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL13924512 | 0.95 | HSD17B10 (0.60) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL13924511 | 0.94 | HSD17B10 (0.63) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20257108 | 0.94 | HSD17B10 (0.63) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL23190432 | 0.90 | MAPT (0.48) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20257105 | 0.89 | TSHR (0.50) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL9343826 | 0.88 | HSD17B10 (0.59) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL3167854 | 0.87 | HRH3 (0.47) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL9506653 | 0.87 | RAB9A (0.45) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL15783716 | 0.86 | HSD17B10 (0.54) | TSHRHSD17B10RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4159258-A | — | — | None | — | — | JP | disclosed |
| JP-9118882-A | — | — | None | — | — | JP | disclosed |
| JP-H09118882-A | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE COMPOSITION | SEIKO EPSON CORP | 1997-05-06 | — | — | JP | disclosed |
| JP-H04159258-A | DIFLUOROBENZONITRILE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AND LIQUID CRYSTAL DISPLAY USING THE COMPOSITION | SEIKO EPSON CORP | 1992-06-02 | — | — | JP | disclosed |