Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778511 | 0.98 | KMT2A (0.44) | KMT2AL3MBTL1HPGDKDM4EHTR1A | |
| SCHEMBL6474960 | 0.87 | KMT2A (0.48) | KMT2AL3MBTL1HPGDKDM4EHTR1A | |
| SCHEMBL10461262 | 0.80 | KMT2A (0.50) | KMT2AL3MBTL1HPGDKDM4EHTR1A | |
| SCHEMBL1575727 | 0.78 | KMT2A (0.52) | KMT2AL3MBTL1HPGDKDM4EHTR1A | |
| SCHEMBL11450595 | 0.78 | KMT2A (0.44) | KMT2AL3MBTL1HPGDKDM4EHTR1A | |
| SCHEMBL20414593 | 0.78 | L3MBTL1 (0.51) | KMT2AL3MBTL1HPGDKDM4EHTR1A | |
| SCHEMBL8955990 | 0.78 | KMT2A (0.48) | KMT2AL3MBTL1HPGDKDM4EHTR1A | |
| SCHEMBL4055640 | 0.78 | KMT2A (0.44) | KMT2AL3MBTL1HPGDKDM4EHTR1A | |
| SCHEMBL9026333 | 0.78 | L3MBTL1 (0.59) | KMT2AL3MBTL1HPGDMAPTMAPK1 | |
| SCHEMBL8778502 | 0.77 | TDP1 (0.54) | KMT2AL3MBTL1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |