Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358952 | 0.85 | KMT2A (0.53) | KMT2AL3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL4055640 | 0.80 | KMT2A (0.44) | KMT2AL3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL20414593 | 0.80 | L3MBTL1 (0.51) | KMT2AL3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL8778511 | 0.80 | KMT2A (0.44) | KMT2AL3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL11450595 | 0.80 | KMT2A (0.44) | KMT2AL3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL8955424 | 0.79 | TDP1 (0.67) | KMT2AL3MBTL1KDM4EALDH1A1TP53 | |
| SCHEMBL27904038 | 0.79 | TDP1 (0.67) | KMT2AL3MBTL1KDM4EALDH1A1TP53 | |
| SCHEMBL10461262 | 0.79 | KMT2A (0.50) | KMT2AL3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL8956162 | 0.78 | L3MBTL1 (0.57) | KMT2AL3MBTL1HPGDALDH1A1TP53 | |
| SCHEMBL8997378 | 0.78 | KDM4E (0.45) | KMT2AL3MBTL1HPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |