Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718291 | 1.00 | TBXA2R (1.00) | TBXA2R | |
| SCHEMBL8918573 | 1.00 | TBXA2R (1.00) | TBXA2R | |
| Bms-180291 SCHEMBL9589119 | 0.99 | TBXA2R (1.00) | TBXA2R | |
| Ifetroban SCHEMBL30218601 | 0.99 | TBXA2R (1.00) | TBXA2R | |
| Bms-180291 SCHEMBL29502980 | 0.99 | TBXA2R (1.00) | TBXA2R | |
| Bms-180291 SCHEMBL28137 | 0.99 | TBXA2R (1.00) | TBXA2R | |
| Bms-180291 SCHEMBL28136 | 0.99 | TBXA2R (1.00) | TBXA2R | |
| Ifetroban SCHEMBL28135 | 0.99 | TBXA2R (1.00) | TBXA2R | |
| Ifetroban SCHEMBL16212975 | 0.98 | TBXA2R (0.98) | TBXA2R | |
| Bms-180291 SCHEMBL16212977 | 0.98 | TBXA2R (0.98) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100889-A | Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1992-03-31 | — | — | US | claimed |
| US-5605917-A | ADMINISTERING A THROMBOXANE A2 RECEPTOR ANTAGONIST | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-02-25 | — | — | US | disclosed |
| US-5153327-A | 7-Oxabicycloheptyl substituted heterocyclic amide or ester prostaglandin analogs useful in the treatment of thrombotic and vasospastic disease | E. R. SQUIBB & SONS, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5100889-A | Thromboxane A2 receptor antagonists, thromboxane synthetase inhibitor | E. R. SQUIBB & SONS, INC. (US) | 1992-03-31 | — | — | US | disclosed |