Bms-180291

Bms-180291

SCHEMBL362595

CCCCCNC(=O)c1coc([C@@H]2[C@@H](Cc3ccccc3CCC(=O)O)[C@@H]3CC[C@H]2O3)n1.[NaH]

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 19/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ifetroban SCHEMBL362594 1.00 TBXA2R (0.98) TBXA2R
Bms-180291 SCHEMBL28190408 1.00 TBXA2R (0.98) TBXA2R
Bms-180291 SCHEMBL28137 0.99 TBXA2R (1.00) TBXA2R
Bms-180291 SCHEMBL29502980 0.99 TBXA2R (1.00) TBXA2R
Ifetroban SCHEMBL30218601 0.99 TBXA2R (1.00) TBXA2R
Bms-180291 SCHEMBL28136 0.99 TBXA2R (1.00) TBXA2R
Ifetroban SCHEMBL28135 0.99 TBXA2R (1.00) TBXA2R
Bms-180291 SCHEMBL9589119 0.99 TBXA2R (1.00) TBXA2R
SCHEMBL8918573 0.98 TBXA2R (1.00) TBXA2R
Ifetroban SCHEMBL16212975 0.98 TBXA2R (0.98) TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1039 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041336-A1 PLATELET REACTIVITY EXPRESSION SCORE PREDICTS CARDIOVASCULAR RISK NEW YORK UNIVERSITY (US) 2026-02-12 US claimed
US-20250049764-A1 Compositions and Methods of Treating Cardiac Fibrosis with Ifetroban CUMBERLAND PHARMACEUTICALS INC. 2025-02-13 US claimed
US-12161632-B2 Compositions and methods of treating cardiac fibrosis with ifetroban CUMBERLAND PHARMACEUTICALS INC. (US) 2024-12-10 US claimed
US-20230270726-A1 Compositions and Methods of Treating Cardiac Fibrosis with Ifetroban VANDERBILT UNIVERSITY 2023-08-31 US claimed
EP-3454850-B1 COMPOSITIONS AND METHODS OF TREATING MUSCULAR DYSTROPHY WITH THROMBOXANE-A2 RECEPTOR ANTAGONISTS CUMBERLAND PHARMACEUTICALS INC (US) 2023-06-21 EP claimed
US-20230129262-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS OF THROMBOXANE A2 RECEPTOR ANTAGONIST FOR THE TREATMENT OF COVID-19 OGLETREE MARTIN (US) 2023-04-27 US claimed
EP-4125882-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS OF THROMBOXANE A2 RECEPTOR ANTAGONIST FOR THE TREATMENT OF COVID-19 Ogletree, Martin (US) 2023-02-08 EP claimed
US-11571412-B2 Thromboxane receptor antagonists in AERD/asthma CUMBERLAND PHARMACEUTICALS INC. (US) 2023-02-07 US claimed
CN-115624549-A Compositions and methods for treating muscular dystrophy using thromboxane-A2 receptor antagonists 坎伯兰医药品股份有限公司 2023-01-20 CN claimed
CN-109152767-B Compositions and methods for treating muscular dystrophy using thromboxane-A2 receptor antagonists 坎伯兰医药品股份有限公司 2022-10-21 CN claimed
CN-1642415-A Palatable oral suspensions and methods of making same BRISTOL MYERS SQUIBB CO (US) 2005-07-20 CN claimed
EP-1482789-A2 PALATABLE ORAL SUSPENSION AND METHOD Bristol-Myers Squibb Company (US) 2004-12-08 EP claimed
EP-1353694-A2 COMBINATIONS OF STEROL ABSORPTION INHIBITOR(S) WITH BLOOD MODIFIER(S) FOR TREATING VASCULAR CONDITIONS Schering Corporation (US) 2003-10-22 EP claimed
US-20030187019-A1 Palatable oral suspension and method TOYAMA CHEMICAL CO., LTD. (JP) 2003-10-02 US claimed
WO-2003077842-A2 PALATABLE ORAL SUSPENSION AND METHOD BRISTOL-MYERS SQUIBB COMPANY (US) 2003-09-25 WO claimed
US-20020147184-A1 Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions SCHERING CORPORATION 2002-10-10 US claimed
WO-2002058734-A2 COMBINATIONS OF STEROL ABSORPTION INHIBITOR(S) WITH BLOOD MODIFIER(S) FOR TREATING VASCULAR CONDITIONS SCHERING CORPORATION (US) 2002-08-01 WO claimed
US-5506248-A SALT OF IFETROBAN AND ONE OR MORE BASIFYING AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1996-04-09 US claimed
CN-1118254-A Pharmaceutical compositions having good dissolution properties BRISTOL MYERS SQIBB COMPANY (US) 1996-03-13 CN claimed
EP-0638310-A1 Pharmaceutical compositions containing ifetroban BRISTOL-MYERS SQUIBB COMPANY (US) 1995-02-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187019-A1 Palatable oral suspension and method TAS2R20, TAS2R60, TAS2R30 TBXA2R 1345/4885
US-20020147184-A1 Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions APOB, FABP2, CYP46A1 TBXA2R 162/4885
US-20260041336-A1 PLATELET REACTIVITY EXPRESSION SCORE PREDICTS CARDIOVASCULAR RISK EPB41L2, MYLK2, RABL3 TBXA2R 2982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.